SR-4559

• Description :

  SR-4559 (Compound 4) is a α/β hydrolase domain-containing protein 5 (ABHD5) ligand. SR-4559 activates adipose triglyceride lipase (ATGL) and stimulates lipolysis by inhibiting ABHD5-PLIN interactions in adipocytes and muscle cells. SR-4559 can be used for metabolic diseases like Chanarin Dorfman syndrome research[1]

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  ATGL

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Metabolic Disease

• Purity :

  98.81

• Smiles :

  O=S(C1=CC=C(OCCO2)C2=C1)(N3CCN(C(CC4=COC5=C4C=CC(C)=C5)=O)CC3)=O

• Molecular Formula :

  C23H24N2O6S

• Molecular Weight :

  456.51

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Lum KM, et al. Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12 (10) :2671-2681.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [847939-23-5]