SR 43845

• Description :

  SR 43845 is a renin inhibitor. SR 43845 decreases blood pressure and inhibits plasma renin activity. SR 43845 can be used for hypertension research[1].

• CAS Number :

  [114037-60-4]

• UNSPSC :

  12352005

• Target :

  Renin

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/sr-43845.html

• Smiles :

  O=C(N[C@@H]([C@H](C)CC)C(NC(CO)(C)CO)=O)C[C@@H](O)[C@H](NC([C@H](NC([C@@H](NC(CCC1=CC=CN=C1)=O)CC2=CC=CC=C2)=O)CC3=CN=CN3)=O)CC4CCCCC4

• Molecular Formula :

  C44H64N8O8

• Molecular Weight :

  833.03

• References & Citations :

  [1]Lacour C, et al. Effects of a renin inhibitor, SR 43845, and of captopril on blood pressure and plasma active renin in conscious sodium-replete macaca. J Hypertens Suppl. 1989 Apr;7 (2) :S33-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2