SR 43845

• Description:

  SR 43845 is a renin inhibitor. SR 43845 decreases blood pressure and inhibits plasma renin activity. SR 43845 can be used for hypertension research[1].

• UNSPSC:

  12352005

• Target:

  Renin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/sr-43845.html

• Smiles:

  O=C (N[C@@H] ([C@H] (C) CC) C (NC (CO) (C) CO) =O) C[C@@H] (O) [C@H] (NC ([C@H] (NC ([C@@H] (NC (CCC1=CC=CN=C1) =O) CC2=CC=CC=C2) =O) CC3=CN=CN3) =O) CC4CCCCC4

• Molecular Formula:

  C44H64N8O8

• Molecular Weight:

  833.03

• References & Citations:

  [1]Lacour C, et al. Effects of a renin inhibitor, SR 43845, and of captopril on blood pressure and plasma active renin in conscious sodium-replete macaca. J Hypertens Suppl. 1989 Apr;7 (2) :S33-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  114037-60-4