SR 43845

CAT: 0804-HY-105259Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-105259Size:1 Each
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Description
SR 43845 is a renin inhibitor. SR 43845 decreases blood pressure and inhibits plasma renin activity. SR 43845 can be used for hypertension research[1].
CAS Number
[114037-60-4]
UNSPSC
12352005
Target
Renin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sr-43845.html
Smiles
O=C(N[C@@H]([C@H](C)CC)C(NC(CO)(C)CO)=O)C[C@@H](O)[C@H](NC([C@H](NC([C@@H](NC(CCC1=CC=CN=C1)=O)CC2=CC=CC=C2)=O)CC3=CN=CN3)=O)CC4CCCCC4
Molecular Formula
C44H64N8O8
Molecular Weight
833.03
References & Citations
[1]Lacour C, et al. Effects of a renin inhibitor, SR 43845, and of captopril on blood pressure and plasma active renin in conscious sodium-replete macaca. J Hypertens Suppl. 1989 Apr;7 (2) :S33-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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