SR 13668

CAT: 0804-HY-16469Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-16469Size:1 Each
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Description
SR13668 is a potent indole analog derived from indole-3-carbinol (I3C), known for its natural anticancer properties but limited by poor metabolic characteristics. Developed to enhance I3C's anticancer efficacy, SR13668 effectively inhibits growth factor-stimulated Akt activation. It demonstrates strong oral anticancer activity across different cancer types in preclinical studies, showing promise in clinical development due to its favorable safety profile and potent therapeutic effects[1].
CAS Number
[637774-61-9]
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sr-13668.html
Smiles
O=C(C1=CC2=C(NC3=C2C=C4C(NC5=C4C=C(C(OCC)=O)C=C5)=C3OC)C=C1)OCC
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
References & Citations
[1]Computer-Aided Rational Drug Design: A Novel Agent (SR13668) Designed to Mimic the Unique Anticancer Mechanisms of Dietary Indole-3-Carbinol to Block Akt Signaling
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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