SR 13668

• Description:

  SR13668 is a potent indole analog derived from indole-3-carbinol (I3C), known for its natural anticancer properties but limited by poor metabolic characteristics. Developed to enhance I3C's anticancer efficacy, SR13668 effectively inhibits growth factor-stimulated Akt activation. It demonstrates strong oral anticancer activity across different cancer types in preclinical studies, showing promise in clinical development due to its favorable safety profile and potent therapeutic effects[1].

• UNSPSC:

  12352005

• Target:

  Akt

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sr-13668.html

• Smiles:

  O=C(C1=CC2=C(NC3=C2C=C4C(NC5=C4C=C(C(OCC)=O)C=C5)=C3OC)C=C1)OCC

• Molecular Formula:

  C25H22N2O5

• Molecular Weight:

  430.45

• References & Citations:

  [1]Computer-Aided Rational Drug Design: A Novel Agent (SR13668) Designed to Mimic the Unique Anticancer Mechanisms of Dietary Indole-3-Carbinol to Block Akt Signaling

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  [637774-61-9]