SR-4370

• Description:

  SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively.

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  HDAC

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/SR-4370.html

• Purity:

  98.38

• Solubility:

  DMSO : ≥ 150 mg/mL

• Smiles:

  O=C (C1=CC=C (C2=CC=CC (F) =C2F) C=C1) NNCCCC

• Molecular Formula:

  C17H18F2N2O

• Molecular Weight:

  304.33

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]LIAO, Daiqing, et al. HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT. WO 2015153516 A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  HDAC1; HDAC2; HDAC3; HDAC6; HDAC8

• CAS Number:

  1816294-67-3