SR-4370

• Description :

  SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  HDAC

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/SR-4370.html

• Purity :

  98.38

• Solubility :

  DMSO : ≥ 150 mg/mL

• Smiles :

  O=C(C1=CC=C(C2=CC=CC(F)=C2F)C=C1)NNCCCC

• Molecular Formula :

  C17H18F2N2O

• Molecular Weight :

  304.33

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]LIAO, Daiqing, et al. HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT. WO 2015153516 A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  HDAC1; HDAC2; HDAC3; HDAC6; HDAC8

• CAS Number :

  [1816294-67-3]