GKA-71

• Description :

  GKA-71 is an orally active Glucokinase activator, possesses an islet protective effect[1].

• UNSPSC :

  12352005

• Target :

  Glucokinase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/gka-71.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC(OC2=CC=C(C=C2)S(=O)(C)=O)=CC(O[C@H](COC)C)=C1)NC3=NC(C)=NS3

• Molecular Formula :

  C21H23N3O6S2

• Molecular Weight :

  477.55

• References & Citations :

  [1]Maria Sörhede Winzell, et al. Chronic glucokinase activation reduces glycaemia and improves glucose tolerance in high-fat diet fed mice. Eur J Pharmacol. 2011 Aug 1;663 (1-3) :80-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [863504-35-2]