GKA-71

• Description:

  GKA-71 is an orally active Glucokinase activator, possesses an islet protective effect[1].

• UNSPSC:

  12352005

• Target:

  Glucokinase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/gka-71.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(OC2=CC=C(C=C2)S(=O)(C)=O)=CC(O[C@H](COC)C)=C1)NC3=NC(C)=NS3

• Molecular Formula:

  C21H23N3O6S2

• Molecular Weight:

  477.55

• References & Citations:

  [1]Maria Sörhede Winzell, et al. Chronic glucokinase activation reduces glycaemia and improves glucose tolerance in high-fat diet fed mice. Eur J Pharmacol. 2011 Aug 1;663 (1-3) :80-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [863504-35-2]