HSD17B13-IN-71

HSD17B13-IN-71

• CAS Number: 2770247-40-8
• UNSPSC Description: HSD17B13-IN-71 (Compound 149) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-71 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
• Target Antigen: 17β-HSD
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/hsd17b13-in-71.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=C(C)C(N=C(C(F)F)N3CC4=C(OC(F)(F)F)C=CC=C4)=C2C3=O
• Molecular Weight: 588.31
• References & Citations: [1]Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported