SM1-71-R

• Description:

  SM1-71-R is a reversible analog o SM1-71 (HY-136848) . SM1-71-R lacks the acrylamide warhead and therefore cannot form a covalent bond with the kinase. SM1-71-R can be used as a control compound for SM1-71[1].

• UNSPSC:

  12352005

• Target:

  Akt

• Related Pathways:

  PI3K/Akt/mTOR

• Field of Research:

  Cancer

• Purity:

  98.70

• Smiles:

  O=C(CC)NC1=C(C=CC=C1)NC2=NC(NC3=CC=C(N(CC4)CCN4C)C=C3)=NC=C2Cl

• Molecular Formula:

  C24H28ClN7O

• Molecular Weight:

  465.98

• References & Citations:

  [1]Rao S, et al. A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers. J Biol Chem. 2019 May 24;294 (21) :8664-8673.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2088180-03-2]