SM1-71-R

• Description :

  SM1-71-R is a reversible analog o SM1-71 (HY-136848) . SM1-71-R lacks the acrylamide warhead and therefore cannot form a covalent bond with the kinase. SM1-71-R can be used as a control compound for SM1-71[1].

• UNSPSC :

  12352005

• Target :

  Akt

• Related Pathways :

  PI3K/Akt/mTOR

• Field of Research :

  Cancer

• Purity :

  98.70

• Smiles :

  O=C(CC)NC1=C(C=CC=C1)NC2=NC(NC3=CC=C(N(CC4)CCN4C)C=C3)=NC=C2Cl

• Molecular Formula :

  C24H28ClN7O

• Molecular Weight :

  465.98

• References & Citations :

  [1]Rao S, et al. A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers. J Biol Chem. 2019 May 24;294 (21) :8664-8673.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2088180-03-2]