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HDAC-IN-71

CAT: 0804-HY-163430Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163430Size:1 Each
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Description
HDAC-IN-71 (Compound 17q) is a potent HDAC inhibitor with IC50 values of 12.6, 14.1, 20, 3, and 72 nM for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC10, respectively. HDAC-IN-71 induces apoptosis and can be used in cancer research[1].
CAS Number
2995354-52-2
UNSPSC
12352005
Target
Apoptosis; HDAC
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-71.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=CC=C1)/C=C2CC(N(C\2=O)CCCCCCC(NO)=O)=O
Molecular Formula
C19H24N2O5
Molecular Weight
360.40
References & Citations
[1]Jiang Q, et al. Discovery of novel itaconimide-based derivatives as potent HDAC inhibitors for the efficient treatment of prostate cancer. Eur J Med Chem. 2024 Apr 5;269:116315.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC10; HDAC2; HDAC3; HDAC6

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