RMM-46

• UNSPSC Description:

  RMM-46 is a selective and reversible covalent inhibitor for MSK/RSK-family kinases[1].

• Target Antigen:

  MAPKAPK2 (MK2)

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/rmm-46.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(/C(C#N)=C/C1=CC2=C(C=C1)NN=C2C3=CC(OC)=C(C(OC)=C3)OC)NC(C)(CO)C

• Molecular Weight:

  450.49

• References & Citations:

  [1]Miller RM, et al. Electrophilic fragment-based design of reversible covalent kinase inhibitors. J Am Chem Soc. 2013 Apr 10;135(14):5298-301.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1307896-46-3