MRS2298

• UNSPSC Description:

  MRS2298 is a potent acyclic P2Y1 receptor antagonist with a Ki of 29.6 nM. MRS2298 inhibits the ADP-induced aggregation of human platelets with an IC50 of 62.8 nM. MRS2298 inhibits Ca2+ rise in platelets with an IC50 of 810 nM[1].

• Target Antigen:

  P2Y Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/mrs2298.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=P(OCC(COP(O)(O)=O)CN1C=NC2=C(N=C(N=C12)Cl)NC)(O)O

• Molecular Weight:

  431.66

• References & Citations:

  [1]Marco Cattaneo, et al. Antiaggregatory activity in human platelets of potent antagonists of the P2Y 1 receptor. Biochem Pharmacol. 2004 Nov 15;68(10):1995-2002.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  491611-43-9