Products for Research Use Only
RegisterLogin

MRS2279 (diammonium)

CAT: 0804-HY-108657ASize: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-108657ASize:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MRS2279 diammonium is a selective and high affinity P2Y1 receptor antagonist, with a Ki value of 2.5 nM and an IC50 value of 51.6 nM. MRS2279 diammonium competitively inhibits ADP-promoted platelet aggregation with an pKb value of 8.05[1][2][3].
CAS Number
2387505-47-5
UNSPSC
12352005
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mrs2279-diammonium.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=[P](O)(O)OC[C@]1([C@H]2O[P](O)(O)=O)[C@]([C@](N3C4=NC(Cl)=NC(NC)=C4N=C3)([H])C2)([H])C1.N.N
Molecular Formula
C13H24ClN7O8P2
Molecular Weight
503.77
References & Citations
[1]Nandanan E, et al. Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y (1) receptor ligands. J Med Chem. 2000;43 (5) :829-842.|[2]Boyer JL, et al, Ravi RG, Jacobson KA, Harden TK. 2-Chloro N (6) -methyl- (N) -methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y (1) receptor antagonist. Br J Pharmacol. 2002;135 (8) :2004-2010.|[3]Wei W, et al. Mechanical ventilation induces lung and brain injury through ATP production, P2Y1 receptor activation and dopamine release. Bioengineered. 2022 Feb;13 (2) :2346-2359.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y1 Receptor

Related Products

CatalogName
HY-108657MRS2279
HY-W590676-01Tetramyristoylcardiolipin (diammonium)
HY-W142308Diammonium dithiodiglycolate
HY-105967A-01Dicresulene (diammonium)
HY-P0118B-01Disitertide (diammonium)
HY-W105775-01Diammonium succinate
HY-110385A-01CGAMP (diammonium)
HY-N6804-01Diammonium Glycyrrhizinate
HY-Y0302-01Diammonium phosphate
HY-146248B-01TFMU-ADPr (diammonium)

Alternative Products

CatalogName
MBS5814876MRS2279 diammonium
T23021-01MRS2279
C6448-25Diammonium Glycyrrhizinate
15580027Diammonium hydrogenphosphate
GTR19190303-01Dicresulene diammonium
GTR19244746-01Diammonium dithiodiglycolate
T19668-01Tiomolibdate diammonium
MBS5817626Disitertide diammonium
MBS5815804cGAMP diammonium
TYD-01440-01Diammonium succinate

Popular Products