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Lamotrigine (isethionate)

CAT: 0804-HY-110032Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-110032Size:1 Each
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Description
Lamotrigine (BW430C) isethionate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine isethionate selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine isethionate can be used for the research of epilepsy, focal seizure, et al[1][2].
CAS Number
113170-86-8
Product Name Alternative
LTG (isethionate) ; BW430C (isethionate)
UNSPSC
12352005
Hazard Statement
H301
Target
Autophagy; Sodium Channel
Type
Reference compound
Related Pathways
Autophagy; Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lamotrigine-isethionate.html
Solubility
10 mM in DMSO
Smiles
O=S(O)(CCO)=O.ClC1=C(Cl)C(C2=C(N)N=C(N)N=N2)=CC=C1
Molecular Formula
C11H13Cl2N5O4S
Molecular Weight
382.22
Precautions
P264-P270-P330-P405-P501
References & Citations
[1]M J Leach, et al. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. Sep-Oct 1986;27 (5) :490-7.|[2]Damianka P Getova, et al. A study of the effects of lamotrigine on mice using two convulsive tests. Folia Med (Plovdiv) . Apr-Jun 2011;53 (2) :57-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4

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