Lamotrigine-13C3
CAT:
804-HY-B0495S4
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Lamotrigine-13C3
- CAS Number: 1188265-38-4
- UNSPSC Description: Lamotrigine-13C3 is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].
- Target Antigen: Autophagy; Sodium Channel
- Type: Isotope-Labeled Compounds
- Related Pathways: Autophagy;Membrane Transporter/Ion Channel
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/lamotrigine-13c3.html
- Solubility: 10 mM in DMSO
- Smiles: N[13C]1=N[13C](N)=NN=[13C]1C2=C(C(Cl)=CC=C2)Cl
- Molecular Weight: 259.07
- References & Citations: [1]M J Leach, et al. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. Sep-Oct 1986;27(5):490-7.|[2]Damianka P Getova, et al. A study of the effects of lamotrigine on mice using two convulsive tests. Folia Med (Plovdiv). Apr-Jun 2011;53(2):57-62.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported