Dalpiciclib (isethionate)

CAT: 0804-HY-114338BSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-114338BSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dalpiciclib (isethionate) is a CDK4/6 inhibitor. Dalpiciclib (isethionate) inhibits the kinase activity of CDK4 and CDK6, thereby blocking the G1-to-S phase transition of the cell cycle and suppressing abnormal cell proliferation. Dalpiciclib (isethionate) can be used for the study of breast cancer[1].
CAS Number
[1980822-14-7]
Product Name Alternative
SHR-6390 (isethionate)
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1C(C(C)=O)=C(C)C2=C(N1C3CCCC3)N=C(NC4=NC=C(C5CCNCC5)C=C4)N=C2.O=S(O)(CCO)=O
Molecular Formula
C27H36N6O6S
Molecular Weight
572.68
References & Citations
[1]ZHU Xiaoyu, et al. Use of Composition Containing CDK4/6 Inhibitor in Combination with Anastrozole in Preparation of Medicament for Treating Tumor Diseases. WO2020/156446 A1. World Intellectual Property Organization (WIPO) . August 6, 2020.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK4; CDK6

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