Lamotrigine

CAT: 0804-HY-B0495-01Size: 500 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-B0495-01Size:500 mg

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Description

Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

CAS Number

84057-84-1

Product Name Alternative

LTG; BW430C

UNSPSC

12352005

Hazard Statement

H301, H319, H336, H361, H362, H410

Target

Autophagy; Sodium Channel

Type

Reference compound

Related Pathways

Autophagy; Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Lamotrigine.html

Concentration

10mM

Purity

99.98

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

NC1=NC(N)=C(C2=CC=CC(Cl)=C2Cl)N=N1

Molecular Formula

C9H7Cl2N5

Molecular Weight

256.09

Precautions

H301, H319, H336, H361, H362, H410

References & Citations

[1]M J Leach, et al. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. Sep-Oct 1986;27 (5) :490-7.|[2]Damianka P Getova, et al. A study of the effects of lamotrigine on mice using two convulsive tests. Folia Med (Plovdiv) . Apr-Jun 2011;53 (2) :57-62.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Launched

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