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Piritrexim (isethionate)

CAT: 0804-HY-167863Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-167863Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Piritrexim isethionate (BW 301U isethionate) is a fat-soluble dihydrofolate reductase inhibitor with activity in the treatment of severe psoriasis. Piritrexim isethionate may be as effective as methotrexate in the treatment of severe psoriasis and may have less hepatotoxicity[1].
CAS Number
79483-69-5
Product Name Alternative
BW 301U (isethionate) ; NSC 351521 (isethionate)
UNSPSC
12352005
Target
Dihydrofolate reductase (DHFR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/piritrexim-isethionate.html
Smiles
O=S(O)(CCO)=O.NC1=NC(N)=NC2=NC=C(CC3=CC(OC)=CC=C3OC)C(C)=C21
Molecular Formula
C19H25N5O6S
Molecular Weight
451.50
References & Citations
[1]A multicentre 12-week open study of a lipid-soluble folate antagonist, piritrexim in severe psoriasis
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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