(E/Z) -BIX02188

• Description :

  (E/Z) -BIX02188 is a MEK5/ERK5 pathway inhibitor. (E/Z) -BIX02188 inhibits the catalytic function of purified MEK5 enzyme. (E/Z) -BIX02188 can be used for the role of MEK5/ERK5 pathway in various biological systems [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/e-z-bix02188.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC=C2C(NC(/C2=C(C3=CC=CC=C3)\NC4=CC=CC(CN(C)C)=C4)=O)=C1)N

• Molecular Formula :

  C25H24N4O2

• Molecular Weight :

  412.48

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Tatake RJ, et al. Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochem Biophys Res Commun. 2008 Dec 5;377 (1) :120-5.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1094614-84-2]