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TGX-155

CAT: 0804-HY-105666Size: 1 EachDry Ice: NoHazardous: No
CAT#: HY-105666Size: 1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TGX-155 (AZ12649385) is a selective inhibitor of PI3Kβ. TGX-155 has potential applications in antithrombotic therapy[1][2][3].
CAS Number
[351071-90-4]
Product Name Alternative
AZ12649385
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tgx-155.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC=CC(OC3=C(C=C(F)C=C3)C)=C2NC(N4CCOCC4)=C1
Molecular Formula
C20H19FN2O3
Molecular Weight
354.37
References & Citations
[1]Verheijen J C, et al. Phosphatidylinositol 3-kinase (PI3K) inhibitors as anticancer drugs[J]. Drugs Future, 2007, 32 (6) : 537-547.|[2]Nylander S, et al. Human target validation of phosphoinositide 3-kinase (PI3K) β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor. J Thromb Haemost. 2012 Oct;10 (10) :2127-36.|[3]Sturgeon SA, et al. Adaptation of the Folts and electrolytic methods of arterial thrombosis for the study of anti-thrombotic molecules in small animals. J Pharmacol Toxicol Methods. 2006 Jan-Feb;53 (1) :20-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kβ

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