SB 204070A

• Description :

  5-HT4 antagonist 3 hydrochloride is a highly selective 5-hydroxytryptamine receptor (5-HT4) antagonist. 5-HT4 antagonist 3 (hydrochloride) blocks muscarine receptors and sodium channels. 5-HT4 antagonist 3 (hydrochloride) can be used to evaluate function of 5-HT4 receptor [1].

• CAS Number :

  [148688-01-1]

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/sb-204070a.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C2OCCOC2=C(N)C(Cl)=C1)OCC3CCN(CCCC)CC3.Cl

• Molecular Formula :

  C19H28Cl2N2O4

• Molecular Weight :

  419.34

• References & Citations :

  [1]Wardle KA, et al. The effects of SB 204070, a highly potent and selective 5-HT4 receptor antagonist, on guinea-pig distal colon. Br J Pharmacol. 1994 Jul;112 (3) :789-94.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported