SB 204070A

• Description:

  5-HT4 antagonist 3 hydrochloride is a highly selective 5-hydroxytryptamine receptor (5-HT4) antagonist. 5-HT4 antagonist 3 (hydrochloride) blocks muscarine receptors and sodium channels. 5-HT4 antagonist 3 (hydrochloride) can be used to evaluate function of 5-HT4 receptor [1].

• UNSPSC:

  12352005

• Target:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sb-204070a.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C2OCCOC2=C(N)C(Cl)=C1)OCC3CCN(CCCC)CC3.Cl

• Molecular Formula:

  C19H28Cl2N2O4

• Molecular Weight:

  419.34

• References & Citations:

  [1]Wardle KA, et al. The effects of SB 204070, a highly potent and selective 5-HT4 receptor antagonist, on guinea-pig distal colon. Br J Pharmacol. 1994 Jul;112 (3) :789-94.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [148688-01-1]