PROTAC PRMT3 degrader 1

• UNSPSC Description:

  PROTAC PRMT3 degrader 1 (compound 11) is a PROTAC degrader targeting PRMT3. PROTAC PRMT3 degrader 1 can inhibit the growth of acute leukemia cells[1].

• Target Antigen:

  Histone Methyltransferase; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-prmt3-degrader-1.html

• Smiles:

  O=C([C@@H]1NC2([C@]3([C@H]1C4=CC=CC(Cl)=C4F)C(NC5=C3C=CC(Cl)=C5)=O)CCCCC2)NCCCCCCCCNC(C6CN(C(CNC(NC7=CC8=C(C=NC=C8)C=C7)=O)=O)C6)=O

• Molecular Weight:

  899.88

• References & Citations:

  [1]Zou W, et al. Discovery of PRMT3 Degrader for the Treatment of Acute Leukemia. Adv Sci (Weinh). 2024 Aug 9:e2405963.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported