PROTAC SOS1 degrader-7

PROTAC SOS1 degrader-7

• CAS Number: 3036155-26-4
• UNSPSC Description: PROTAC SOS1 degrader-7 (Example 15) is a SOS1 PROTAC degrader. PROTAC SOS1 degrader-7 has anti-tumor activity . (Pink: SOS1 ligand (HY-163583); Black: linker (HY-163584); Blue: E3 ligase ligand (HY-W454906))[1].
• Target Antigen: PROTACs; Ras
• Type: Reference compound
• Related Pathways: GPCR/G Protein;MAPK/ERK Pathway;PROTAC
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-sos1-degrader-7.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=NN=C(C2=C1C=NC(N3CCN(CC3)C(C4CCN(CC4)CC5CCC6(CCN(CC6)C(C7=CC(N8CCC(NC8=O)=O)=C(C=C7)C)=O)CC5)=O)=C2)N[C@@H](C9=CC=CC(C(F)F)=C9C)C
• Molecular Weight: 919.12
• References & Citations: [1]Zhengqing Ye, et al. Sos1 protein degradation agent and use thereof. WO2024083257A1.2024-04-25.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported