PROTAC SOS1 degrader-7

• UNSPSC Description:

  PROTAC SOS1 degrader-7 (Example 15) is a SOS1 PROTAC degrader. PROTAC SOS1 degrader-7 has anti-tumor activity . (Pink: SOS1 ligand (HY-163583); Black: linker (HY-163584); Blue: E3 ligase ligand (HY-W454906))[1].

• Target Antigen:

  PROTACs; Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;MAPK/ERK Pathway;PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-sos1-degrader-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=NN=C(C2=C1C=NC(N3CCN(CC3)C(C4CCN(CC4)CC5CCC6(CCN(CC6)C(C7=CC(N8CCC(NC8=O)=O)=C(C=C7)C)=O)CC5)=O)=C2)N[C@@H](C9=CC=CC(C(F)F)=C9C)C

• Molecular Weight:

  919.12

• References & Citations:

  [1]Zhengqing Ye, et al. Sos1 protein degradation agent and use thereof. WO2024083257A1.2024-04-25.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3036155-26-4