U-48520

• Description :

  U-48520 is an agonist for μ-opioid receptor with EC50 of 1561 nM[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302+H312+H332

• Target :

  Opioid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/u-48520.html

• Smiles :

  O=C(N([C@H]1[C@H](N(C)C)CCCC1)C)C2=CC=C(Cl)C=C2

• Molecular Formula :

  C16H23ClN2O

• Molecular Weight :

  294.82

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

• References & Citations :

  [1]Otte L, et al., Investigation of the μ- and κ-opioid receptor activation by eight new synthetic opioids using the [35 S]-GTPγS assay: U-47700, isopropyl U-47700, U-49900, U-47931E, N-methyl U-47931E, U-51754, U-48520, and U-48800. Drug Test Anal. 2022 Jul;14 (7) :1187-1199.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  μ Opioid Receptor/MOR

• CAS Number :

  [67579-11-7]