hCAIX-IN-18

hCAIX-IN-18

• CAS Number: 2925261-76-1
• UNSPSC Description: hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with Kis of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, hCAIX, hCAXII, respectively. hCAIX-IN-18 can be used for cancer research[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcaix-in-18.html
• Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)
• Smiles: ClC1=CC=C(/C(N2CCN(C3=CC=C(S(=O)(N)=O)C=C3)CC2)=N\O)C=C1
• Molecular Weight: 394.88
• References & Citations: [1]1. Peerzada MN, et al. Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors. ACS Med Chem Lett. 2023 May 8;14(6):810-819.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported