Thymidine phosphorylase

• Description:

  Thymidine phosphorylase is a nucleoside metabolism enzyme that plays an important role in the pyrimidine salvage pathway. Thymidine phosphorylase catalyzes the conversion of thymidine to thymine and 2-deoxy-α-D-ribose-1-phosphate (dRib-1-P) . Thymidine phosphorylase plays an important role in platelet activation in vitro and thrombosis in vivo by participating in multiple signaling pathways. Thymidine phosphorylase can be used for the study of myocardial infarction, stroke, pulmonary embolism and cancer[1].

• UNSPSC:

  12352204

• Target:

  Phosphorylase

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer; Neurological Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/thymidine-phosphorylase.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Thymidinephosphorylase]

• References & Citations:

  [1]Elamin YY, et al. Thymidine Phosphorylase in Cancer; Enemy or Friend? Cancer Microenviron. 2016 Apr;9 (1) :33-43. |[2]Li W, et al. Thymidine phosphorylase: A potential new target for treating cardiovascular disease. Trends Cardiovasc Med. 2018 Apr;28 (3) :157-171. doi: 10.1016/j.tcm.2017.10.003.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at 4°C for 2 years

• Scientific Category:

  Enzyme

• Clinical Information:

  No Development Reported

• CAS Number:

  [9030-23-3]