Thymidine phosphorylase

CAT: 0804-HY-P2916Size: 1 KUDry Ice: NoHazardous: No
CAT#:0804-HY-P2916Size:1 KU
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Description
Thymidine phosphorylase is a nucleoside metabolism enzyme that plays an important role in the pyrimidine salvage pathway. Thymidine phosphorylase catalyzes the conversion of thymidine to thymine and 2-deoxy-α-D-ribose-1-phosphate (dRib-1-P) . Thymidine phosphorylase plays an important role in platelet activation in vitro and thrombosis in vivo by participating in multiple signaling pathways. Thymidine phosphorylase can be used for the study of myocardial infarction, stroke, pulmonary embolism and cancer[1].
CAS Number
[9030-23-3]
UNSPSC
12352204
Target
Phosphorylase
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/thymidine-phosphorylase.html
Solubility
10 mM in DMSO
Smiles
[Thymidinephosphorylase]
References & Citations
[1]Elamin YY, et al. Thymidine Phosphorylase in Cancer; Enemy or Friend? Cancer Microenviron. 2016 Apr;9 (1) :33-43. |[2]Li W, et al. Thymidine phosphorylase: A potential new target for treating cardiovascular disease. Trends Cardiovasc Med. 2018 Apr;28 (3) :157-171. doi: 10.1016/j.tcm.2017.10.003.
Shipping Conditions
Room Temperature
Storage Conditions
Store at 4°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported

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