Thymidine (Standard)

• Description :

  Thymidine (Standard) is the analytical standard of Thymidine. This product is intended for research and analytical applications. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

• CAS Number :

  [50-89-5]

• Product Name Alternative :

  DThyd (Standard) ; NSC 21548 (Standard)

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  DNA/RNA Synthesis; Endogenous Metabolite; Orthopoxvirus; Reference Standards

• Type :

  Reference Standards

• Related Pathways :

  Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/thymidine-standard.html

• Purity :

  99.98

• Smiles :

  O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1CO

• Molecular Formula :

  C10H14N2O5

• Molecular Weight :

  242.23

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8 (17) .|[2]FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181 (4604) :274-5.FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181 (4604) :274-5.|[3]Izeradjene K, et al. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independentdeletion of superantigen-reactive peripheral T cells. Int Immunol. 2001 Jan;13 (1) :85-93.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C, sealed storage, away from light and moisture

• Scientific Category :

  Reference Standards