Thymidine (Standard)

• Description:

  Thymidine (Standard) is the analytical standard of Thymidine. This product is intended for research and analytical applications. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

• Product Name Alternative:

  DThyd (Standard) ; NSC 21548 (Standard)

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  DNA/RNA Synthesis; Endogenous Metabolite; Orthopoxvirus; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/thymidine-standard.html

• Purity:

  99.98

• Smiles:

  O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1CO

• Molecular Formula:

  C10H14N2O5

• Molecular Weight:

  242.23

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8 (17) .|[2]FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181 (4604) :274-5.FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181 (4604) :274-5.|[3]Izeradjene K, et al. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independentdeletion of superantigen-reactive peripheral T cells. Int Immunol. 2001 Jan;13 (1) :85-93.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C, sealed storage, away from light and moisture

• Scientific Category:

  Reference Standards

• CAS Number:

  [50-89-5]