Thymidine-15N2

CAT: 0804-HY-N1150S9-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N1150S9-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Thymidine-15N2 is the 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].
Product Name Alternative
DThyd-15N2; NSC-15N2
UNSPSC
12352005
Target
DNA/RNA Synthesis; Endogenous Metabolite; Orthopoxvirus
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thymidine-15n2.html
Purity
99.0
Solubility
10 mM in DMSO|DMSO : 50mg/mL (ultrasonic)
Smiles
O=C1[15N](C=C(C([15NH]1)=O)C)[C@]2([H])O[C@@H]([C@H](C2)O)CO
Molecular Formula
C10H14 15N2O5
Molecular Weight
244.22
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8 (17) .; FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181 (4604) :274-5.|[3]FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181 (4604) :274-5.|[4]Izeradjene K, et al. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independentdeletion of superantigen-reactive peripheral T cells. Int Immunol. 2001 Jan13 (1) :85-93.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W766305Thymidine-13C,15N2
HY-N1150S8Thymidine-13C10,15N2
HY-W392933SThymidine 5'-monophosphate-15N2
HY-W392933S2Thymidine 5'-monophosphate-15N2 (dilithium)
HY-W392933S1Thymidine 5'-monophosphate-15N2, d13 (dilithium)
HY-W392933S4-01Thymidine 5'-monophosphate-13C10,15N2 (dilithium)
HY-128738SThymidine-5'-monophosphate-13C10,15N2 (disodium)
HY-W7500353',5'-Di-p-toluate Thymidine-13C,15N2
HY-W010450S2-01Thymine-15N2
HY-W747214-01Thymine-15N2,13C

Alternative Products

CatalogName
021813Thymidine-13C,15N2
sc-301901Thymidine-13C10,15N2 5'-triphosphate sodium salt solution
TRC-D679417-50MG3',5'-Di-p-toluate Thymidine-13C,15N2
sc-224344Uracil-15N2
TRC-U830053-25MGUridine-15N2
TRC-C952503-5MGCyanamide-15N2
OR1037097Xanthine-15N2
sc-251411Urea-15N2
sc-220427α-Carboline-15N2
sc-237098Thiourea-15N2

Popular Products