STING antagonist-2

• Description:

  STING antagonist-2 (Compound 50) is a potent STING antagonist with a pIC50 of 8.9. STING antagonist-2 has the potential for immunity research[1].

• UNSPSC:

  12352005

• Target:

  STING

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sting-in-6.html

• Purity:

  99.73

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CN(/C1=N\C(C2=CC(C)=NN2CC)=O)C3=CC(C(N)=O)=CC=C3N1C/C(C)=C(C)/CN4C5=C(OCC6=CC(OC)=CC=C6)C=C(C(N)=O)C=C5N(/C4=N\C(C7=CC(C)=NN7CC)=O)C

• Molecular Formula:

  C46H52N12O6

• Molecular Weight:

  868.98

• References & Citations:

  [1]David T. Fosbenner, et al. Modulators of stimulator of interferon genes (sting) . WO2019069270A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2305940-34-3]