TEAD-IN-2

• Description :

  TEAD-IN-2 is a novel, orally active inhibitor of transcriptional enhancer associate domain (TEAD) and modulates TEAD by ubiquitination and/or degradation by compounds. TEAD-IN-2 can be used for the research of a variety of diseases, disorders or conditions associated with TEAD[1].

• UNSPSC :

  12352005

• Target :

  YAP

• Type :

  Reference compound

• Related Pathways :

  Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/tead-in-2.html

• Purity :

  98.14

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  FC(C1=CC=C(CN2CCC(C3CC(Br)=NO3)CC2)C=C1)(F)F

• Molecular Formula :

  C16H18BrF3N2O

• Molecular Weight :

  391.23

• References & Citations :

  [1]Alfredo C. Castro, et al. Preparation of heterocyclic compounds as TEAD degraders and uses thereof. Patent wo2022120355A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2563849-97-6]