TEAD-IN-2

CAT: 0804-HY-147088-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-147088-01Size:5 mg
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Description
TEAD-IN-2 is a novel, orally active inhibitor of transcriptional enhancer associate domain (TEAD) and modulates TEAD by ubiquitination and/or degradation by compounds. TEAD-IN-2 can be used for the research of a variety of diseases, disorders or conditions associated with TEAD[1].
CAS Number
[2563849-97-6]
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tead-in-2.html
Purity
98.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(C1=CC=C(CN2CCC(C3CC(Br)=NO3)CC2)C=C1)(F)F
Molecular Formula
C16H18BrF3N2O
Molecular Weight
391.23
References & Citations
[1]Alfredo C. Castro, et al. Preparation of heterocyclic compounds as TEAD degraders and uses thereof. Patent wo2022120355A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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