TEAD-IN-11

• Target:

  YAP

• Related Pathways:

  Stem Cells

• Bioactivity:

  TEAD-IN-11 (compound 38) exhibits potent inhibitory activity against TEAD1 (IC 50 = 8.7 nM), TEAD2 (IC 50 = 3.4 nM), and TEAD3 (IC 50 = 5.6 nM), demonstrating selectivity for these isoforms as a covalent inhibitor. This compound is valuable for cancer research.

• Smiles:

  O=C (C=C) N1CCC (C#CC2=CC=C (C=C2) C (F) (F) F) C1

• Molecular Formula:

  C16H14F3NO

• Molecular Weight:

  293.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3032196-88-3