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TEAD-IN-11

CAT: 0931-T87984-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T87984-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3032196-88-3
Target
YAP
Related Pathways
Stem Cells
Bioactivity
TEAD-IN-11 (compound 38) exhibits potent inhibitory activity against TEAD1 (IC 50 = 8.7 nM), TEAD2 (IC 50 = 3.4 nM), and TEAD3 (IC 50 = 5.6 nM), demonstrating selectivity for these isoforms as a covalent inhibitor. This compound is valuable for cancer research.
Smiles
O=C(C=C)N1CCC(C#CC2=CC=C(C=C2)C(F)(F)F)C1
Molecular Formula
C16H14F3NO
Molecular Weight
293.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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