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TEAD-IN-9

CAT: 0804-HY-161443Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161443Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TEAD-IN-9 (compound 17) is a TEAD1 inhibitor with an IC50 of 0.29 μM. TEAD-IN-9 targets the palmitoyl pocket of TEAD, thereby effectively inhibiting the binding of YAP-TEAD and blocking the transcriptional function of YAP-TEAD[1].
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tead-in-9.html
Solubility
10 mM in DMSO
Smiles
O=P(C)(C)C1=CC=C(NCC2=CC=C(C(F)(F)F)C=C2)C(C3=NC(OC4COC4)=CC=N3)=C1
Molecular Formula
C23H23F3N3O3P
Molecular Weight
477.42
References & Citations
[1]Dong Liu. Small molecule compound having phosphorylated aryl structure, and use thereof. WO2024061366A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TEAD

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