TEAD-IN-11
CAT:
804-HY-161569
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TEAD-IN-11
- CAS Number: 3032196-88-3
- UNSPSC Description: TEAD-IN-11 (compound 38) has a good inhibitory effect on TEAD1 (IC50=8.7 nM), TEAD2 (IC50=3.4 nM), TEAD3 (IC50=5.6 nnM). TEAD-IN-11 has good selective activity against TEAD1-3 as a covalent inhibitor. TEAD-IN-11 can be used for cancer research[1].
- Target Antigen: YAP
- Type: Reference compound
- Related Pathways: Stem Cell/Wnt
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tead-in-11.html
- Solubility: 10 mM in DMSO
- Smiles: FC(F)(F)C1=CC=C(C#CC2CN(C(C=C)=O)CC2)C=C1
- Molecular Weight: 293.28
- References & Citations: [1]Henry William, et al. Yap/taz-tead oncoproteins inhibitors.WO2024059317A1.2023-09-15
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported