BMS-566394

• UNSPSC Description:

  BMS-566394 is a potent inhibitor of tumor necrosis factor-α (TNF-α) converting enzyme (TACE) that helps reduce the production of TNF-α, thereby alleviating inflammation and immune-mediated diseases and can be used in the study of inflammatory and autoimmune diseases[1].

• Target Antigen:

  TNF Receptor

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Inflammation/Immunology; Others

• Assay Protocol:

  https://www.medchemexpress.com/bms-566394.html

• Smiles:

  O=C(N[C@H](CCOC1)[C@H]1C(NO)=O)C(C=C2)=CC=C2CN3C(C(F)(F)F)=NC4=CC=CC=C34

• Molecular Weight:

  462.42

• References & Citations:

  [1]Sengupta P, et al. Synthesis, preliminary biological evaluation and molecular modeling of some new heterocyclic inhibitors of TACE[J]. European journal of medicinal chemistry, 2011, 46(11): 5549-5555.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  503166-51-6