Ac-DEVDD-TPP

• Description :

  Ac-DEVDD-TPP is a porphyrin derivative that can be converted into D-TPP by caspase-3 cleavage and laser irradiation. The formed porphyrin nanofibers can effectively induce Apoptosis and Pyroptosis. Ac-DEVDD-TPP has antitumor activity[1].

• UNSPSC :

  12352209

• Target :

  Apoptosis; Pyroptosis

• Type :

  Peptides

• Related Pathways :

  Apoptosis; Immunology/Inflammation

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ac-devdd-tpp.html

• Smiles :

  OC(C[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(NC1=CC=C(C=C1)/C2=C(C=C3)/N=C3/C(C4=CC=CC=C4)=C(C=C/5)\NC5=C(C6=CC=CC=C6)/C(C=C/7)=NC7=C(C8=CC=CC=C8)/C9=CC=C2N9)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C68H64N10O14

• Molecular Weight :

  1245.29

• References & Citations :

  [1]Liu X, et al. Apoptosis-Amplified Assembly of Porphyrin Nanofiber Enhances Photodynamic Therapy of Oral Tumor. J Am Chem Soc. 2023 Apr 12;145 (14) :7918-7930.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [2950171-24-9]