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TPP-Ce6

CAT: 0931-T87996-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T87996-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3030629-73-0
Target
Reactive Oxygen Species|||Apoptosis|||Others
Related Pathways
Apoptosis|||Immunology/Inflammation|||NF-?B|||Others|||Metabolism
Bioactivity
TPP-Ce6 is a mitochondria-targeting photosensitizer formed by the ester linkage of chlorin e6 (Ce6) with triphenylphosphine (TPP) . Upon light exposure, TPP-Ce6 generates reactive oxygen species (ROS), particularly singlet oxygen, which induce oxidative stress, leading to mitochondrial dysfunction and apoptosis (cellular apoptosis) . This compound is useful for research on mitochondrial roles in apoptosis, energy metabolism, and cancer treatment.
Smiles
[P+](CCOC(=O)C1=C2C(CC(OCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O)=C6[C@@H](CCC(OCC[P+](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9)=O)[C@H](C)C(=N6)C=C%10NC(=CC%11=NC(=CC(=C1C)N2)C(CC)=C%11C)C(C=C)=C%10C)(C%12=CC=CC=C%12)(C%13=CC=CC=C%13)C%14=CC=CC=C%14
Molecular Formula
C94H90N4O6P33+
Molecular Weight
1464.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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