ABBV-712
CAT:
804-HY-156409-01
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ABBV-712
- CAS Number: 2368945-27-9
- UNSPSC Description: ABBV-712 is a selective inhibitor of Tyrosine kinase 2 (TYK2), with IC50 of 0.195 μM, that play important role in autoimmune diseases[1].
- Target Antigen: JAK
- Type: Reference compound
- Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/abbv-712.html
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: CC(NC1=CC2=C(C=N1)N(C=C2C3=NC([C@]4(COCC4)OC)=CC(COC)=C3)C5COC5)=O
- Molecular Weight: 452.50
- References & Citations: [1]Eric Breinlinger, et al. Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712. J Med Chem. 2023 Oct 26;66(20):14335-14356.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported