FTY720-Mitoxy

FTY720-Mitoxy

• CAS Number: 1604816-11-6
• UNSPSC Description: FTY720-Mitoxy is a fingolimod hydrochloride (HY-12005) derivative with neuroprotective and PP2A activating activities. FTY720-Mitoxy has the property of targeting mitochondria. In addition, FTY720-Mitoxy protects neurons by reducing inflammatory responses and is used in the study of neurodegenerative diseases such as Parkinson's disease[1].
• Target Antigen: Phosphatase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/fty720-mitoxy.html
• Smiles: O=C(NC(CO)(CO)CCC1=CC=C(CCCCCCCC)C=C1)CC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]
• Molecular Weight: 704.72
• References & Citations: [1]Vargas-Medrano J, et al. Novel FTY720-based compounds stimulate neurotrophin expression and phosphatase activity in dopaminergic cells[J]. ACS Medicinal Chemistry Letters, 2014, 5(7): 782-786.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported