FTY720-Mitoxy

• Description :

  FTY720-Mitoxy is a fingolimod hydrochloride (HY-12005) derivative with neuroprotective and PP2A activating activities. FTY720-Mitoxy has the property of targeting mitochondria. In addition, FTY720-Mitoxy protects neurons by reducing inflammatory responses and is used in the study of neurodegenerative diseases such as Parkinson's disease[1].

• CAS Number :

  [1604816-11-6]

• UNSPSC :

  12352005

• Target :

  Phosphatase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/fty720-mitoxy.html

• Smiles :

  O=C(NC(CO)(CO)CCC1=CC=C(CCCCCCCC)C=C1)CC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]

• Molecular Formula :

  C40H51BrNO3P

• Molecular Weight :

  704.72

• References & Citations :

  [1]Vargas-Medrano J, et al. Novel FTY720-based compounds stimulate neurotrophin expression and phosphatase activity in dopaminergic cells[J]. ACS Medicinal Chemistry Letters, 2014, 5 (7) : 782-786.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported