MitoPQ

CAT: 0804-HY-130278-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-130278-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study[1].
CAS Number
[1821370-28-8]
Product Name Alternative
MitoParaquat
UNSPSC
12352005
Hazard Statement
H301, H311, H331
Target
ROS Kinase
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mitopq.html
Purity
99.91
Solubility
DMSO : 33.33 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
C[N+]1=CC=C(C=C1)C2=CC=[N+](C=C2)CCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.[I-].[I-].[I-]
Molecular Formula
C39H46I3N2P
Molecular Weight
954.48
Precautions
H301, H311, H331
References & Citations
[1]Robb EL, et al. Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat. Free Radic Biol Med. 2015 Dec;89:883-94.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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