(R) -FTY720-OMe

• Description:

  (R) -FTY720-OMe is a selective SphK2 inhibitor with an IC50 of 16.5 μM. (R) -FTY720-OMe can be used for cancer, fibrosis, and Alzheimer’s and sickle cell diseases research[1].

• UNSPSC:

  12352005

• Target:

  SphK

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer; Neurological Disease; Cardiovascular Disease

• Smiles:

  COC[C@@](CO)(N)CCC1=CC=C(C=C1)CCCCCCCC

• Molecular Formula:

  C20H35NO2

• Molecular Weight:

  321.50

• References & Citations:

  [1]Congdon MD, et al. Structure-Activity Relationship Studies and Molecular Modeling of Naphthalene-Based Sphingosine Kinase 2 Inhibitors. ACS Med Chem Lett. 2016 Feb 2;7 (3) :229-34.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  SphK2

• CAS Number:

  [1382486-90-9]