AG 1517

• Background:

  AG 1517 is a potent and selective ATP competitive inhibitor of the epidermal growth factor receptor tyrosine kinase EGFR.

• Description:

  EGFR kinase inhibitor

• Product Name Alternative:

  4-[ (3-Bromophenyl) amino]-6,7-dimethoxyquinazoline hydrochloride, AG 1517, PD 153035, SU 5271, ZM 252868, PD 153,035, SU 5271, 4- (3-Bromoanilino) -6,7-dimethoxyquinazoline

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥98% (TLC)

• Weight:

  0.025

• Format:

  White to off-white solid

• Solubility:

  Soluble in DMSO

• Molecular Formula:

  C16H14BrN3O2

• Molecular Weight:

  360.2

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Kunkel M.W., et al. (1996) Investigational New Drugs. 13(4): 295–302.

• CAS Number:

  153436-54-5