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AG-1517 · HCl

CAT: 0498-bs-82211C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82211C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation1. Inhibits the growth of a number of cancer cell lines2. An extremely useful tool for exploring EGF-mediated cellular signaling3.
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
RT

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