AG 879

• Background :

  A879 is a selective inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. It also inhibits ErbB2 and VEGFR-2.

• Description :

  NGFR kinase inhibitor

• Product Name Alternative :

  Tyrphostin AG 879, α-Cyano- (3,5-di-t-butyl-4-hydroxy) thiocinnamide

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity :

  ≥99% (TLC)

• Weight :

  0.025

• Format :

  Yellow solid

• Solubility :

  Soluble in 100% ethanol (25 mg/ml) or DMSO (25 mg/ml)

• Molecular Formula :

  C18H24N2OS

• Molecular Weight :

  316.5

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. He H., et al. (2004) Cancer Biol. Therapy. 3(1): 96–101. 2. Ohmichi M., et al. (1993) Biochem. 32(17): 4650–4658.

• CAS Number :

  148741-30-4