AG 879

CAT: 0400-SIH-429-25MGSize: 25 mgDry Ice: NoHazardous: No

CAT#:0400-SIH-429-25MGSize:25 mg

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Background

A879 is a selective inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. It also inhibits ErbB2 and VEGFR-2.

Description

NGFR kinase inhibitor

CAS Number

148741-30-4

Product Name Alternative

Tyrphostin AG 879, α-Cyano- (3,5-di-t-butyl-4-hydroxy) thiocinnamide

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥99% (TLC)

Weight

0.025

Format

Yellow solid

Solubility

Soluble in 100% ethanol (25 mg/ml) or DMSO (25 mg/ml)

Molecular Formula

C18H24N2OS

Molecular Weight

316.5

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. He H., et al. (2004) Cancer Biol. Therapy. 3(1): 96–101. 2. Ohmichi M., et al. (1993) Biochem. 32(17): 4650–4658.

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