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AChE-IN-58

CAT: 0804-HY-N12622Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N12622Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AChE-IN-58 (Compound 3) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-58 can extend the mean lifespan, delay the Aβ1-42-induced paralysis, enhanc the locomotion, and alleviate glutamic acid (Glu) -induced neurotoxicity of CL4176 worms[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-58.html
Solubility
10 mM in DMSO
Smiles
OC1=C(O)C(O)=CC(C(OC2=CC(O)=C([C@@]3([H])CCC(N3CC)=O)C(O)=C24)=C(O)C4=O)=C1
Molecular Formula
C21H19NO9
Molecular Weight
429.38
References & Citations
[1]Chen CH, et al. Novel Flavonol Alkaloids in Green Tea: Synthesis, Detection, and Anti-Alzheimer's Disease Effect in a Transgenic Caenorhabditis elegans CL4176 Model. J Agric Food Chem. 2024 Feb 21;72 (7) :3695-3706.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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