SB-258585

• Description :

  SB-258585 is a selective ligand with high affinity for the 5-HT6 receptor, with a pKi value of 8.53[1].

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/sb-258585.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S(C1=CC=C(I)C=C1)(NC2=CC=C(OC)C(N3CCN(C)CC3)=C2)=O

• Molecular Formula :

  C18H22IN3O3S

• Molecular Weight :

  487.36

• References & Citations :

  [1]Hirst WD, et al. Characterization of [ (125) I]-SB-258585 binding to human recombinant and native 5-HT (6) receptors in rat, pig and human brain tissue. Br J Pharmacol. 2000;130 (7) :1597-1605.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT6 Receptor

• CAS Number :

  [209480-63-7]