SB-258585

• Description:

  SB-258585 is a selective ligand with high affinity for the 5-HT6 receptor, with a pKi value of 8.53[1].

• UNSPSC:

  12352005

• Target:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sb-258585.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=C(I)C=C1)(NC2=CC=C(OC)C(N3CCN(C)CC3)=C2)=O

• Molecular Formula:

  C18H22IN3O3S

• Molecular Weight:

  487.36

• References & Citations:

  [1]Hirst WD, et al. Characterization of [ (125) I]-SB-258585 binding to human recombinant and native 5-HT (6) receptors in rat, pig and human brain tissue. Br J Pharmacol. 2000;130 (7) :1597-1605.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  5-HT6 Receptor

• CAS Number:

  [209480-63-7]