SB-258585

• UNSPSC Description:

  SB-258585 is a selective ligand with high affinity for the 5-HT6 receptor, with a pKi value of 8.53[1].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sb-258585.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=C(I)C=C1)(NC2=CC=C(OC)C(N3CCN(C)CC3)=C2)=O

• Molecular Weight:

  487.36

• References & Citations:

  [1]Hirst WD, et al. Characterization of [(125)I]-SB-258585 binding to human recombinant and native 5-HT(6) receptors in rat, pig and human brain tissue. Br J Pharmacol. 2000;130(7):1597-1605.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  209480-63-7