SB-656104

• UNSPSC Description:

  SB-656104 is a potent antagonist of 5-HT7 receptor, with the pKi of 8.70, blocking 5-carboxamidotryptamine (5-CT) stimulated adenylyl cyclase activity[1].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sb-656104.html

• Smiles:

  O=S(N1[C@H](CCC1)CCN2CCC(CC2)OC3=CC=C(C=C3)Cl)(C4=CC=C(C=CN5)C5=C4)=O

• Molecular Weight:

  488.04

• References & Citations:

  [1]Ian T Forbes, et al. SB-656104-A: a novel 5-HT7 receptor antagonist with improved in vivo properties. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3341-4.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  446020-51-5