Thyroxine sulfate

• Description:

  Thyroxine sulfate is a thyroid hormone metabolite.

• Product Name Alternative:

  T4 Sulfate

• UNSPSC:

  12352005

• Target:

  Drug Metabolite; Endogenous Metabolite; Thyroid Hormone Receptor

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/Thyroxine_sulfate.html

• Purity:

  99.84

• Solubility:

  DMSO : 140 mg/mL (ultrasonic)

• Smiles:

  N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(OS(=O)(O)=O)C(I)=C2)C(O)=O

• Molecular Formula:

  C15H11I4NO7S

• Molecular Weight:

  856.93

• References & Citations:

  [1]Wu SY, et al. Identification of thyroxine-sulfate (T4S) in human serum and amniotic fluid by a novel T4S radioimmunoassay. Thyroid. 1992 Summer;2 (2) :101-5.|[2]Rutgers M, et al. Effects of propylthiouracil on the biliary clearance of thyroxine (T4) in rats: decreased excretion of 3,5,3'-triiodothyronine glucuronide and increased excretion of 3,3',5'-triiodothyronine glucuronide and T4 sulfate. Endocrinology. 1989 Oct;125 (4) :2175-86.|[3]Peeters RP, et al. Increased thyroxine sulfate levels in critically ill patients as a result of a decreased hepatic type Ideiodinase activity. J Clin Endocrinol Metab. 2005 Dec;90 (12) :6460-5.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  77074-49-8