D-Thyroxine (sodium)

CAT: 0804-HY-A0152ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-A0152ASize:1 Each
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Description
D-thyroxine (D-T4) sodium is an orally active thyroid hormone that inhibits the secretion of TSH. D-thyroxine sodium can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-thyroxine sodium can be used for the study of hypercholesterolemia[1][2][3].
CAS Number
[137-53-1]
Product Name Alternative
D-T4 (sodium)
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/d-thyroxine-sodium.html
Solubility
10 mM in DMSO
Smiles
N[C@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)C(O[Na])=O
Molecular Formula
C15H10I4NNaO4
Molecular Weight
798.85
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]John J. Schrogie M.D., et al. II. The effect of D-thyroxine, clofibrate, and norethandrolone. Clinical Pharmacology and Therapeutics, Volume8, Issue1part1 January 1967 Pages 70-77|[2]Raluca-IoanaStefan, et al. Simultaneous determination of l-thyroxine (l-T4), d-thyroxine (d-T4), and l-triiodothyronine (l-T3) using a sensors/sequential injection analysis system.|[3]TUCKER RG. The biologic effects of D-thyroxine. A review. Angiology. 1962 Feb;13:85-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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