D-Thyroxine (sodium)

• Description:

  D-thyroxine (D-T4) sodium is an orally active thyroid hormone that inhibits the secretion of TSH. D-thyroxine sodium can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-thyroxine sodium can be used for the study of hypercholesterolemia[1][2][3].

• Product Name Alternative:

  D-T4 (sodium)

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H312-H332

• Target:

  Thyroid Hormone Receptor

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/d-thyroxine-sodium.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N[C@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)C(O[Na])=O

• Molecular Formula:

  C15H10I4NNaO4

• Molecular Weight:

  798.85

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations:

  [1]John J. Schrogie M.D., et al. II. The effect of D-thyroxine, clofibrate, and norethandrolone. Clinical Pharmacology and Therapeutics, Volume8, Issue1part1 January 1967 Pages 70-77|[2]Raluca-IoanaStefan, et al. Simultaneous determination of l-thyroxine (l-T4), d-thyroxine (d-T4), and l-triiodothyronine (l-T3) using a sensors/sequential injection analysis system.|[3]TUCKER RG. The biologic effects of D-thyroxine. A review. Angiology. 1962 Feb;13:85-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [137-53-1]