Biotin- (L-Thyroxine)

CAT: 0804-HY-18341FSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-18341FSize:1 Each
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Description
Biotin- (L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341) . L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine, T3) from Biotin- (L-Thyroxine) (T4) [1].
CAS Number
[149734-00-9]
UNSPSC
12171500
Target
Endogenous Metabolite; Thyroid Hormone Receptor
Type
Dye Reagents
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/biotin-l-thyroxine.html
Solubility
10 mM in DMSO
Smiles
IC(C=C1C[C@@H](C(O)=O)NC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=C(C(I)=C1)OC4=CC(I)=C(C(I)=C4)O
Molecular Formula
C25H25I4N3O6S
Molecular Weight
1003.17
References & Citations
[1]Arici M, et al. Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients. Endocr J. 2018 Mar 28;65 (3) :317-323.|[2]Corriveau S, et al. Levothyroxine treatment generates an abnormal uterine contractility patterns in an in vitro animalmodel. J Clin Transl Endocrinol. 2015 Sep 9;2 (4) :144-149.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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