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ML-792

CAT: 0804-HY-108702-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-108702-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50 values of 3 and 11 nM, respectively) compared with NAE/NEDD8 and UAE/ubiquitin (IC50> values of 32 μM and >100 μM, respectively) [1].
CAS Number
1644342-14-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ml-792.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=NN(CC4=CC=CC(Br)=C4)C=C3)=O)C1)(N)=O
Molecular Formula
C21H23BrN6O5S
Molecular Weight
551.41
Precautions
H302, H315, H319, H335
References & Citations
[1]He X, et al. Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor. Nat Chem Biol. 2017 Nov;13 (11) :1164-1171.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
BA7370-5ML-792
BM171106-01ML 792
A16832-5ML-792 5mg
A16832-2ML-792 2mg
A16832-100ML-792 100mg
A16832-25ML-792 25mg
A16832-10ML-792 10mg
A16832-50ML-792 50mg
A16832-1ML-792 1mg
A16832-10mM-DML-792 10mM * 1mL in DMSO

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