ML 083

CAT: 0804-HY-111936Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-111936Size:1 Each
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Description
ML083 is a member of a series of highly specific allosteric activators for the tumor-specific isoform of human pyruvate kinase (M2 isoform) . ML083 affects the cooperativity of phosphoenolpyruvate (PEP) binding. ML083 can be used in the research of tumors[1].
CAS Number
[562867-96-3]
Product Name Alternative
BML283
UNSPSC
12352005
Target
Pyruvate Kinase
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=S(N1CCN(S(=O)(C2=CC=C(OCCO3)C3=C2)=O)CC1)(C4=CC=C(OC)C=C4)=O
Molecular Formula
C19H22N2O7S2
Molecular Weight
454.52
References & Citations
[1]Auld D, et al. Identification of activators for the M2 isoform of human pyruvate kinase. Probe Reports from the NIH Molecular Libraries Program [Internet], 2010.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PKM2

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