ML 083

• Description :

  ML083 is a member of a series of highly specific allosteric activators for the tumor-specific isoform of human pyruvate kinase (M2 isoform) . ML083 affects the cooperativity of phosphoenolpyruvate (PEP) binding. ML083 can be used in the research of tumors[1].

• Product Name Alternative :

  BML283

• UNSPSC :

  12352005

• Target :

  Pyruvate Kinase

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Smiles :

  O=S(N1CCN(S(=O)(C2=CC=C(OCCO3)C3=C2)=O)CC1)(C4=CC=C(OC)C=C4)=O

• Molecular Formula :

  C19H22N2O7S2

• Molecular Weight :

  454.52

• References & Citations :

  [1]Auld D, et al. Identification of activators for the M2 isoform of human pyruvate kinase. Probe Reports from the NIH Molecular Libraries Program [Internet], 2010.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PKM2

• CAS Number :

  [562867-96-3]