MI-503

CAT: 0804-HY-16925-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0804-HY-16925-01Size:2 mg
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Description
MI-503 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.
CAS Number
[1857417-13-0]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MI-503.html
Purity
99.87
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(N(CC5=CNN=C5)C(C#N)=C6)C6=C4C)CC3
Molecular Formula
C28H27F3N8S
Molecular Weight
564.63
Precautions
H315, H319, H335
References & Citations
[1]Borkin D, et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 2015 Apr 13;27 (4) :589-602.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
BUP09934-01MI-503
A20975-50MI-503 50mg
A20975-200MI-503 200mg
A20975-5MI-503 5mg
A20975-100MI-503 100mg
A20975-2MI-503 2mg
A20975-10MI-503 10mg
A20975-25MI-503 25mg
A20975-10mM-DMI-503 10mM * 1mL in DMSO
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